| AE | Ammunition and Explosives |
| AEA | Atomic Energy Act |
| AG | Australia Group |
| ASME | American Society of Mechanical Engineers |
| AT | Anti-Terrorism |
| ATF | Alcohol, Tobacco, and Firearms |
| AVLIS | Atomic Vapor Laser Isotope Separation |
| BATF&E | Bureau of Alcohol, Tobacco, Firearms and Explosives |
| BIS | Bureau of Industry and Security |
| BWC | Biological and Toxins Weapons Convention |
| CB | Chemical/Biological |
| CBRNe | Chemical, Biological, Radiological, nuclear, and explosive |
| CC | Crime Control |
| CCL | Commerce Control List |
| CCLI | Commerce Control List Item |
| COTS | Commercial Off-the-Shelf |
| CW | Weapons |
| CWC | Chemical Weapons Convention |
| D&D | Destruction and Dismantlement |
| DDTC | Office of Defense Trade Controls |
| DEA | Drug Enforcement Agency |
| DEAR | Department of Energy Acquisition Regulations |
| DEMIL | Demilitarization Manual |
| DHS | Department of Homeland Security |
| DLA | Defense Logistics Agency |
| DOC | Department of Commerce |
| DOD | Department of Defense |
| DOE | Department of Energy |
| DOS | Department of State |
| DTRA | Defense Threat Reduction Agency |
| EAR | Export Administration Regulations |
| EC | Export Control |
| ECCN | Export Control Classification Number |
| ECCO | Export Control Coordinators Organization |
| ECI | Export Controlled Technology Information |
| EDP | Especially Designed or Prepared |
| EFD | Exception from Destruction |
| EI | Encryption Item |
| EPA | Environmental Protection Agency |
| EU/EU | End-use/end user |
| FC | Firearms Convention |
| FDA | Food and Drug Administration |
| FLETC | Federal Law Enforcement Training Centers |
| FRD | Formerly Restricted Data |
| GSA | General Services Administration |
| HEU | Highly Enriched Uranium |
| HFIR | High Flux Isotope Reactor |
| HR | High Risk |
| IAEA | International Atomic Energy Agency |
| INL | Idaho National Laboratory |
| ITAR | International Traffic in Arms Regulations |
| LANL | Los Alamos National Laboratory |
| LBNL | Lawrence Berkeley National Laboratory |
| LLNL | Lawrence Livermore National Laboratory |
| LPR | Lawful Permanent Resident |
| MCTL | Military Critical Technologies List |
| MLI | Munitions List Item |
| MLIS | Molecular Laser Isotope Separation |
| MT | Missile Technology |
| MTCR | Missile Technology Control Regime |
| NATO | North Atlantic Treaty Organization |
| NE | Nuclear Science and Technology |
| NLR | No License Required |
| NNPI | Naval Nuclear Propulsion Information |
| NNSA | National Nuclear Security Administration |
| NP | Nuclear Proliferation |
| NPT | Nuclear Nonproliferation Treaty |
| NRC | Nuclear Regulatory Commission |
| NS | National Security |
| NSG | Nuclear Suppliers Group |
| OFAC | Department of Treasury (Office of Foreign Assets Control) |
| OPMO | Organizational Property Management Officer |
| OPCW | Organization for the Prohibition of Chemical Weapons |
| ORNL | Oak Ridge National Laboratory |
| OUO | Official Use Only |
| PSP | Plasma Separation Process |
| RD | Restricted Data |
| RS | Regional Stability |
| SD | Specially Designed |
| SI | Significant Item |
| SL | Surreptitious Licensing |
| SME | Subject Matter Expert |
| SME | Significant Military Equipment |
| SNL | Sandia National Laboratories |
| SNM | Special Nuclear Material |
| SS | Short Supply |
| STA | Strategic Trade Authorization |
| STI | Scientific and Technical Information |
| UAV | Unmanned Aerial Vehicle |
| UCNI | Unclassified Controlled Nuclear Information |
| UN | UN Sanctions |
| USG | United States Government |
| USML | United States Munitions List |
| WA | Wassenaar Arrangement |
| WIPP | Waste Isolation Pilot Plant |
| WMD | Weapon of Mass Destruction |
| XP | Computers |